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In cells containing less topoisomerase IIα fewer DNA strand breaks will be produced
Momelotinib also causes the inhibition of cell proliferation in cell lines constitutively activated by JAK2 or MPL signaling
Bilal Ahmad
Remibrutinib inhibits BTK activity with an IC50 value of 0
SAR405 R enantiomer Catalog No.:M24141-C In cells containing less topoisomeraseSAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is a PIK3C3 Vps34 inhibitor. Product information CAS Number: 1946010 79 2 Molecular Weight: 443. 85 Formula: C19H21ClF3N5O2 Chemical Name: (2R) 1 [(5 chloropyridin 3 yl)methyl] 8 [(3R) 3 methylmorpholin 4 yl] 2 (trifluoromethyl) 1H,2H,3H,4H,6H pyrimido[1,2 a][1,3]diazin 6 one Smiles: C[C@@H]1COCCN1C1=CC(=O)N2CC[C@@H](N(CC3=CN=CC(Cl)=C3)C2=N1)C(F)(F)F InChiKey: SPDQRCUBFSRAFI
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