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Chemical Name: 2-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3
administration of 50 and 100 mg/kg SNS-314 Mesylate results a dose-dependent inhibition of histone H3 phosphorylation
and PAX6 protein expression
Next-generation epidermal growth factor receptor tyrosine kinase inhibitors in epidermal growth factor receptor -mutant non-small cell lung cancer
Hydralazine Hydrochloride atinine Chemical Name: 2-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3Hydralazine Hydrochloride is a direct acting vasodilator that is used as an antihypertensive agent. Hydralazine Hydrochloride alters intracellular calcium release and interferes with smooth muscle cell calcium influx, resulting in arterial vasodilatation. This agent also inhibits the phosphorylation of myosin protein and chelation of trace metals required for smooth muscle contraction, resulting in an increase in heart rate, stroke volume and cardiac
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