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CN(C)CC/C=C1/C2=CC=CC=C2SC2=CC=C(Cl)C=C2/1
J Neural Transm Suppl
Perry S Brignola
4-diyn-1-ium-3
K-Ras ligand-Linker Conjugate 2 rcetrapib CN(C)CC/C=C1/C2=CC=CC=C2SC2=CC=C(Cl)C=C2/1K Ras ligand Linker Conjugate 2 incorporates a ligand for K Ras, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K Ras ligand Linker Conjugate 2 can be used in the synthesis of PROTAC K Ras Degrader 1 (HY 129523), which is potent PROTAC K Ras degrader that exhibits 70% degradation efficacy in SW1573 cells. Product information Molecular Weight: 822. 99 Formula: C45H58N8O7 Chemical Name: benzyl (2S) 4 [2 [[(2S, 4R) 4 [2
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