![PHA-767491 Hydrochloride - CAS# 942425-68-5 noxerine ]pentadeca-1(15)](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M11199_1621563155.gif?v=1742884880)
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]pentadeca-1(15)
GS 5734-metabolite
TAK-875 has no agonist potency to other members of the FFA receptor family with EC50 >10 μM
KB-R7943 inhibits high glucose-induced endothelial ICAM-1 expression and monocyte-endothelial adhesion
PHA-767491 Hydrochloride - CAS# 942425-68-5 noxerine ]pentadeca-1(15)PHA 767491, also known as CAY10572, is a potent, ATP competitive dual cdc7 cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication. PHA 767491 Suppresses Hepatocarcinoma Synergistically with 5 Fluorouracil. PHA 767491 in combination with 5 FU exhibited much stronger cytotoxicity and induced significant apoptosis manifested by remarkably increased caspase 3 activation and poly(ADP Ribose) polymerase
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