WAY-213613 yl-PEG6-alcohol Aβ/tau aggregation-IN-1 with N-methylation of

Aβ/tau aggregation-IN-1 with N-methylation of the quinolone ring effectively inhibits Aβ1-42 aggregation by 84

MSSA: methicillin-sensitive S

6R)-3-(acetyloxy)-4-(dimethylamino)-6-methyloxan-2-yl]oxy}-12-{[(2R

Chrysosplenetin significantly augments the rat plasma level and anti-malarial efficacy of ART

WAY-213613 yl-PEG6-alcohol Aβ/tau aggregation-IN-1 with N-methylation ofWAY 213613 is a potent, selective nonsubstrate reuptake inhibitor of GLT 1 EAAT2 with IC50 of 85 nM EAAT2. It displays 59 and 44 fold selectivity over EAAT1 and EAAT3 (IC50s are 5 and 3. 8 M, respectively). WAY 213613 shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function. Product information CAS Number: 868359 05 1 Molecular Weight: 415. 19 Formula: C16H13BrF2N2O4 Chemical