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CCG-63808 metabolite Hydroxy Iloperidone Moxifloxacin has activity against mycobacteria

SKU: 61847424852

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Description

Moxifloxacin has activity against mycobacteria in addition to M

Chemical Name: N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine hydrochloride

PubMed PMID: 30799261

PubMed Central PMCID: PMC2791573

CCG-63808 metabolite Hydroxy Iloperidone Moxifloxacin has activity against mycobacteriaCCG 63808 is a potent and reversible RGS protein inhibitor. Regulators of G protein signalling (RGS) are major determinants of metabotropic receptor activity, reducing the lifespan of the GTP bound state of G proteins. Inhibition of spinal RGS4 restored endogenous analgesic signalling pathways and mitigated neuropathic pain. Signalling through CB1 receptors may be involved in this beneficial effect. Product information CAS Number: 620113 73 7

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