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InChi: InChI=1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9
(+)-Curcumenol
is angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure
breast cancer cell lines MCF-7
Hydroxyzine pamoate ne-5'-diphosphate trisodium InChi: InChI=1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9Hydroxyzine pamoate is a histamine H1 receptor antagonist. Target: Histamine H1 ReceptorHydroxyzine inhibits carbachol (10 M) induced serotonin release by 34% at 10 M, by 25% 1 M and by 17% 0. 1 M in pretreated bladder slices for 60 min . Hydroxyzine (0. 1 mM) treatment inhibits the progression and severity of EAE by 50% and the extent of mast cell degranulation by 70% in Lewis rats with allergic encephalomyelitis (EAE) . Hydroxyzine (500 M)
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