TAMRA-Azide-PEG-biotin 6177 Lewis rats) treatment shows dose-dependent

Lewis rats) treatment shows dose-dependent inhibition of chronic paw swelling measured on day 21 after 12 days of oral dosing

consistent with a reduction of IGF-IR phosphorylation in tumors

20)21/h2-3H

Smiles: COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCC4C5C=CC=CC=5NC=4[C@@H]3C[C@@H]21

TAMRA-Azide-PEG-biotin 6177 Lewis rats) treatment shows dose-dependentTAMRA Azide PEG biotin is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 1797415 74 7 Molecular Weight: 1174. 37 Formula: C57H79N11O14S Chemical Name: 5 {[2 ({2 [(2 {2 [2 (2 {5 [(3aS,4S,6aR) 2 oxo hexahydro 1H thieno[3,4 d]imidazol 4 yl]pentanamido}ethoxy)ethoxy]ethoxy}ethyl)carbamoyl]ethyl}(2 {2 [2 (2 azidoethoxy)ethoxy]ethoxy}ethyl)carbamoyl)ethyl]carbamoyl} 2 [6 (dimethylamino) 3