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Chymase-IN-1 10740 Chemical Name: (2S)-6-amino-N-[(1S)-1-{[(1R)-1-carbamoyl-2-sulfanylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]-2-acetamidohexanamide

SKU: 83137101929

4.1
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Description

Chemical Name: (2S)-6-amino-N-[(1S)-1-{[(1R)-1-carbamoyl-2-sulfanylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]-2-acetamidohexanamide

is selectively cytotoxic to human pulmonary carcinoid and small cell lung carcinoma cells

Wuweizichun-A

The first Lineweaver–Burk plot is constructed in the absence of inhibitor

Chymase-IN-1 10740 Chemical Name: (2S)-6-amino-N-[(1S)-1-{[(1R)-1-carbamoyl-2-sulfanylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]-2-acetamidohexanamideChymase IN 1 is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase with an IC50 of 29 nM. Product information CAS Number: 862090 74 2 Molecular Weight: 431. 83 Formula: C20H15ClNO4PS Chemical Name: [(5 chloro 1 benzothiophen 3 yl)[(naphthalen 2 yl)carbamoyl]methyl]phosphonic acid Smiles: OP(O)(=O)C(C1=CSC2=CC=C(Cl)C=C12)C(=O)NC1=CC2=CC=CC=C2C=C1 InChiKey: HUJXISJLAPAFBO UHFFFAOYSA N InChi: InChI=1S C20H15ClNO4PS c21 14

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