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Aurora B is a positive regulator of mitosis that functions in the attachment of the mitotic spindle to the centromere
PubMed PMID: 27294323
Smiles: C[C@H](OC1=CC(=CN=C1N)C1=CN(N=C1)C1CCNCC1)C1=C(Cl)C=CC(F)=C1Cl
CH4O3S/c1-19-11-24-5-7-28-20(2)12-26(45-28)9-10-40-17-33-36(51-40)37-38(50-33)39(52-40)35-29(49-37)8-6-25(47-35)13-22(42)14-27-31(16-30(46-24)21(19)3)48-32(34(27)44-4)15-23(43)18-41
Piceatannol - CAS# 10083-24-6 035TING-Inducer-1 Aurora B is a positivePiceatannol is a selective inhibitor of protein tyrosine kinase Syk. It could inhibit ICa, L, Ito, IKr, Ca2+ transients and Na+ Ca2+ exchange except IK1. Shows multiple biological activities such as anti inflammatory, antiproliferative and immunomodulatory effects. In vitro: The treatment of human myeloid cells with piceatannol suppressed TNF induced DNA binding activity of NF B. The effect of piceatannol was not restricted to myeloid cells, as TNF
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